2018 has been a rewarding year for Strok@lliance as a result of several projects completed and new models that have been developed! Here is a brief summary of the key points regarding our development and achievements:

  • Strok@lliance is proud to count new clients from mid-size to top 10 pharma companies.
  • Several new tailor-made models have been added to our catalogue according to customers request including:

→ A double autologous blood injection in cisterna magna, a complex model of subarachnoidian hemorrhage in rat.

→ Models of ischemia-reperfusion in juvenile rats (28 days) enabling Strok@lliance to predict the effects related to drug administration on children.

  • Strok@lliance obtained a grant from French research ministry to start a CIFRE Thesis. The Thesis will start in spring 2019 and will focused on the refinement of our thrombin-induced stroke models by the addition of comorbidities (aging, hypertension, diabetes…).
  • Strok@lliance team is growing with the recruitment of new technicians, empowering us to carry out more and more projects with the same level of quality and efficiency.

After these past two years, Strok@lliance is pursuing its objective of becoming a reference as the preclinical CRO dedicated to stroke with an increasingly number of projects planned for 2019.

Our team is grateful for the trust customers placed in us to design and validate stroke models, as well as to carry out their pre-clinical studies. We are committed to provide services of quality and are constantly evolving to answer customer specific demands.

Strok@lliance is pleased to announce the acquisition of ISO 9001 certification based on the standard from 2015.
 
Through an internal and external Audit of the OFC (the French Certification Organization): quality assurance, control and monitoring procedures have been carried out to attest to the quality of our services.
 
By being accredited, our company is insuring the customers to meet their expectations by the quality of its management system in the following areas: consulting, advising and expertise of studies in the field of in vitro and in vivo preclinical research.
 
 

Impact of Bradykinin Generation During Thrombolysis in Ischemic Stroke

A very interesting review have been published by our Caen academic partner (PhIND unit, Université de Caen Normandie / INSERM ) concerning the current evidence linking tPA mediated thrombolysis, bradykinin generation and potential subsequent neurovascular damages. While tPA is an important pharmacological tool for acute stroke management, this clot buster also promotes hemorrhagic transformation, symptomatic cerebral edema and angioedema. Preclinical and clinical evidence suggests that intravenous thrombolysis generates large amounts of bradykinin, a peptide with potent pro-inflammatory, and pro-edematous effects. Thus, this tPA-induced generation of bradykinin is a potential target to improve neurological outcome after thrombolysis.

Link to the article

JOIN US!

 

Strok@lliance is growing to provide its customers with high level and original services in preclinical stroke studies.

You have now the opportunity to join a young and dynamic team looking for challenge in a high level scientific and technologic environment !

 

Strok@lliance invites applications from eligible candidates for recruitment of a Scientific Laboratory Technician in stroke preclinical testing.

The company is looking for individuals who wants to contribute their skills to provide excellent work in a challenging and rewarding environment.

 

Find the application details here.